FAPI: Fast and Accurate P-value Imputation for genetic association
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 

Links of MX Li's tools:

 

FAPI is a powerful multi-thread Java-based application developed to infer p-values of untyped Single-nucleotide polymorphisms (SNPs) through p-values of SNPs in LD with the untyped one. With similar imputation accuracy to other genotype imputation tools (including IMPUTE and MACH), FAPI is superfast, without requiring phases of reference genotypes and any sample raw genotypes.

  
Currently FAPI has three main function:
 

Impute p-value

Example

Meta-anlaysis

Example

Assese Quality

Example
FAPI V0.1 has been released! Donwload it! and See Online Manual

Advantages of FAPI :
  • Superfast
  • No need genotypes of original samples
  • Accurate
Comments and suggestions are welcome, please e-mail limx54@yahoo.com
Reference:
    Kwan JS^, Li MX^*, Deng JE, Sham PC*.FAPI: Fast and Accurate P-value Imputation for genome-wide association study. Eur J Hum Genet. 2016 May;24(5):761-6. doi: 10.1038/ejhg.2015.190. PubMed
   
 
 

Miao-xin Li, Jia-en Deng, Center for Genomic Sciences & Department of Psychiatry, The University of Hong Kong, All rights reserved.